Description

Benzyl-2,3,4,5,6-D5-Amine CAS NO 1219802-81-9 is a deuterated analog of benzylamine, where five hydrogen atoms on the aromatic ring are replaced with deuterium (D), a stable hydrogen isotope. This high isotopic purity makes it an essential internal standard and tracer in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily used by researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science for metabolic studies, degradation pathway analysis, and kinetic isotope effect investigations.

Application

• Internal Standard for LC-MS/MS: Used in the quantitative bioanalysis of pharmaceuticals and their metabolites to improve accuracy and precision.
• Metabolic Pathway Tracing: Employed in drug discovery and development to study absorption, distribution, metabolism, and excretion (ADME) profiles.
• Degradation Studies: Acts as a tracer to elucidate environmental or in-vivo degradation pathways of chemicals and agrochemicals.
• Kinetic Isotope Effect (KIE) Research: Utilized in mechanistic studies to understand reaction pathways and enzyme mechanisms.
• NMR Spectroscopy: Serves as a useful probe in nuclear magnetic resonance studies due to the distinct properties of deuterium.
• Pharmaceutical Impurity Profiling: Helps in the identification and quantification of process-related impurities and degradants.
• Material Science Research: Used in the synthesis of deuterated polymers or liquid crystals for specialized optical and electronic applications.

Basic Information

Product Name	Benzyl-2,3,4,5,6-D5-Amine
CAS No.	1219802-81-9
Molecular Formula	C7H2D5N
Molecular Weight	113.17 g/mol
Synonyms	Benzyl-d5-amine; (2,3,4,5,6-Pentadeuteriophenyl)methanamine; α-Aminotoluene-d5; Phenylmethyl-d5-amine; Deutero-Benzylamine; Benzylamine-2,3,4,5,6-d5; Bzl-d5-NH2; Monodeuterated Benzylamine (ring-d5)
EINECS	Contact for details

Quality Control

Every batch of Benzyl-2,3,4,5,6-D5-Amine is produced and tested under strict quality management protocols to ensure exceptional isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity by HPLC, and identity confirmation. Our quality system is designed to meet the rigorous demands of analytical and synthetic applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % D)	≥ 98.0% (on the aromatic ring)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.