Description

Bezafibrate-D6 (Dimethyl-D6) is a stable isotope-labeled analog of the lipid-regulating agent bezafibrate, specifically deuterated at the two methyl positions. This high-purity reference standard is essential for ensuring accuracy and reliability in quantitative analytical methods. It is primarily used by pharmaceutical research and development laboratories, clinical diagnostic facilities, and contract research organizations (CROs) for applications requiring precise internal standardization.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical quantitative reference in the bioanalysis of bezafibrate and its metabolites in biological matrices like plasma and urine.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking and quantification of the parent drug during ADME (Absorption, Distribution, Metabolism, and Excretion) research.
• Clinical Research and Therapeutic Drug Monitoring (TDM): Used in method development and validation for assays monitoring drug levels in patients.
• Pharmaceutical Quality Control: Supports impurity profiling and assay validation of bezafibrate in active pharmaceutical ingredient (API) and finished dosage forms.
• Environmental and Food Safety Testing: Applicable in trace analysis for detecting pharmaceutical residues in environmental water samples or food products.

Basic Information

Product Name	Bezafibrate-D6 (Dimethyl-D6)
CAS No.	1219802-74-0
Molecular Formula	C19H14D6ClNO4
Molecular Weight	367.85 g/mol
Synonyms	2-[4-[2-[(3-Carboxypropyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoic-3,3,4,4,5,5-d6 acid; Bezafibrate (dimethyl-d6); Bezafibrate-d6; Deuterated Bezafibrate; Isotopically Labeled Bezafibrate; 2-[4-[2-[(3-Carboxypropyl)carbamoyl]ethyl]phenoxy]-2-methylpropanoic-3,3,4,4,5,5-d6 acid
EINECS	Contact for details

Quality Control

Every batch of Bezafibrate-D6 (Dimethyl-D6) is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and MS. A Certificate of Analysis (COA) detailing batch-specific results for identity, purity (HPLC), isotopic enrichment, and residual solvents is provided with each shipment to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (Deuterium Content)	≥98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.