Description

Sodium Dl-Lactate-D3 is a deuterium-labeled isotopologue of sodium lactate, a key biochemical salt. This compound is specifically designed for use as an internal standard in quantitative analytical techniques, providing enhanced precision and accuracy in metabolic and pharmacokinetic studies. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors who require high-fidelity isotopic tracers for mass spectrometry (LC-MS/MS, GC-MS) and NMR spectroscopy.

Application

• Quantitative Mass Spectrometry: Serves as a critical internal standard for the precise quantification of lactate and related metabolites in complex biological matrices like plasma, serum, and cell culture media.
• Metabolic Pathway Tracing: Used in stable isotope labeling experiments to investigate glycolysis, gluconeogenesis, and the Cori cycle in cellular and in vivo models.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables accurate tracking of drug metabolism and disposition when lactate is a relevant metabolite or biomarker.
• Clinical Diagnostics Development: Facilitates the development and validation of high-sensitivity assays for conditions like lactic acidosis, sepsis, and mitochondrial disorders.
• Nutritional and Sports Science Research: Applied in studies monitoring lactate turnover and energy metabolism in athletes and nutritional interventions.
• Biopharmaceutical Manufacturing: Can be used in process analytical technology (PAT) to monitor lactate levels in fermentation and cell culture processes.

Basic Information

Product Name	Sodium Dl-Lactate-D3
CAS No.	1219802-24-0
Molecular Formula	C3H2D3NaO3
Molecular Weight	116.07 g/mol (approximate)
Synonyms	Sodium 2-hydroxypropanoate-2,3,3,3-d4; Sodium DL-Lactate-d3; Sodium (±)-Lactate-d3; Deuterated Sodium Lactate; Sodium Lactate (D3); 2-Hydroxypropionic-2,3,3,3-d4 Acid Sodium Salt; DL-Lactic-2,3,3,3-d4 Acid Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of Sodium Dl-Lactate-D3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and Mass Spectrometry to confirm deuteration level and positional purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting assay, isotopic enrichment, and impurity profiles to ensure consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Chemical Purity (Titration)	95.0 - 105.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.