Description

3-Cyanobenzyl-D6 Bromide is a deuterium-labeled organic bromide compound, serving as a crucial stable isotope-labeled building block in advanced chemical synthesis. Its primary value lies in enabling precise metabolic and pharmacokinetic studies by acting as an internal standard in mass spectrometry, ensuring analytical accuracy and reliability. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries developing novel compounds and diagnostic tools.

Application

• Pharmaceutical Research & Development: As a deuterium-labeled internal standard for the accurate quantification of metabolites and active pharmaceutical ingredients (APIs) using LC-MS and GC-MS.
• Metabolic Pathway Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of molecules within biological systems without isotopic interference.
• Synthetic Chemistry Intermediate: A key building block for the synthesis of more complex deuterated compounds, including potential drug candidates and specialty chemicals.
• Analytical Method Development: Critical for developing and validating highly sensitive and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Agrochemical Research: Employed in the study of environmental fate, degradation pathways, and residue analysis of pesticides and herbicides.
• Forensic and Clinical Toxicology: Enhances the precision of assays designed to detect and quantify drugs, toxins, and biomarkers in complex matrices.

Basic Information

Product Name	3-Cyanobenzyl-D6 Bromide
CAS No.	1219802-21-7
Molecular Formula	C8D6BrN
Molecular Weight	213.09 g/mol
Synonyms	α,α,α,2,4,6-D6-3-Cyanobenzyl Bromide; (3-Cyanophenyl)-D6-methyl Bromide; 3-(Bromomethyl-D6)benzonitrile; m-Cyanobenzyl-D6 Bromide; Deuterated 3-Cyanobenzyl Bromide; 3-Cyanobenzyl Bromide-d6; Benzonitrile, 3-(bromomethyl-D6)-; 1219802-21-7
EINECS	Contact for details

Quality Control

Our 3-Cyanobenzyl-D6 Bromide is manufactured under strict quality systems to ensure the high isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic enrichment (D-atom %), and impurity profile. We adhere to relevant industry standards for stable isotope-labeled compounds, and custom synthesis to meet specific purity or enrichment specifications is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-atom %)	≥98.0% (by MS)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.