Description

3-Chloropropionic--D4 Acid is a deuterium-labeled isotopologue of 3-chloropropionic acid, serving as a critical internal standard and tracer in advanced analytical chemistry. This compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry, particularly for metabolic and pharmacokinetic studies. It is primarily needed by pharmaceutical R&D laboratories, agrochemical developers, and academic research institutions focused on isotope dilution analysis and mechanistic pathway elucidation.

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in LC-MS and GC-MS for the precise quantification of 3-chloropropionic acid and related metabolites.
• Pharmaceutical Research: Critical tracer in drug metabolism and pharmacokinetics (DMPK) studies to track absorption, distribution, metabolism, and excretion (ADME) pathways.
• Agrochemical Development: Employed in environmental fate studies and residue analysis of chlorinated propionate herbicides.
• Biochemical Research: Serves as a probe in enzymatic and metabolic pathway studies involving chlorinated carboxylic acids.
• Chemical Synthesis: Used as a labeled building block for the synthesis of deuterated complex molecules for research purposes.
• Forensic and Doping Control: Enhances the accuracy of confirmatory testing for specific banned or controlled substances.

Basic Information

Product Name	3-Chloropropionic--D4 Acid
CAS No.	1219802-17-1
Molecular Formula	C3D4ClO2
Molecular Weight	127.53 g/mol (approx.)
Synonyms	3-Chloropropionic-2,2,3,3-d4 Acid; Deuterated 3-Chloropropionic Acid; [2,2,3,3-2H4]-3-Chloropropanoic Acid; 3-Chloro[2,2,3,3-2H4]propionic Acid; 3-Chloropropanoic-d4 Acid; β-Chloropropionic-d4 Acid; DL-3-Chloropropionic-2,2,3,3-d4 Acid
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality protocols to ensure isotopic purity and chemical integrity, which are paramount for analytical applications. Each batch is characterized by NMR, Mass Spectrometry, and HPLC to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic purity (e.g., D% > 98 atom %), and impurity profile is provided with every shipment to support your regulatory and research documentation.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and should be stored in a cool, dry place, ideally at 2-8°C for long-term stability. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.