Description

2,5-Di-(tert-Butyl-D9)-4-Methoxyphenol-3,6-D2 is a deuterated isotopologue of the common antioxidant butylated hydroxyanisole (BHA). This compound is specifically designed for use as an internal standard in advanced analytical chemistry, providing unmatched precision for quantitative analysis. It is essential for researchers and quality control laboratories in the pharmaceutical, food science, and material stability sectors who require high-fidelity data for method development and regulatory compliance.

Application

• Analytical Internal Standard: Primary use as a deuterated standard for the accurate quantification of BHA and related phenolic antioxidants via GC-MS or LC-MS.
• Pharmaceutical Research: Enables precise pharmacokinetic and metabolic stability studies of antioxidant-containing drug formulations.
• Food & Beverage Analysis: Critical for testing and ensuring compliance with regulations concerning synthetic antioxidant levels in food products and edible oils.
• Polymer & Material Science: Used to study the degradation kinetics and effectiveness of antioxidant additives in plastics, rubbers, and fuels.
• Method Development & Validation: Serves as a key reference material for developing and validating robust analytical methods in contract research organizations (CROs) and testing labs.
• Stability-Indicating Assays: Facilitates the development of assays to monitor the stability and shelf-life of products containing phenolic antioxidants.

Basic Information

Product Name	2,5-Di-(tert-Butyl-D9)-4-Methoxyphenol-3,6-D2
CAS No.	1219802-07-9
Molecular Formula	C15D20O2
Molecular Weight	240.41 g/mol
Synonyms	BHA-d20; Deuterated Butylated Hydroxyanisole; 2,5-Di-(tert-butyl-d9)-4-methoxyphenol-3,6-d2; 3-tert-Butyl-d9-4-hydroxyanisole-2,5-di-tert-butyl-d9-d2; 2,5-Di-tert-butyl-4-methoxyphenol-d20; Isotopically Labeled BHA; Internal Standard BHA-d20; (3,5-Bis(1,1-dimethylethyl-d9)-4-methoxyphenol-3,6-d2)
EINECS	Contact for details

Quality Control

Every batch of 2,5-Di-(tert-Butyl-D9)-4-Methoxyphenol-3,6-D2 is manufactured and tested to meet the stringent requirements for isotopic purity and chemical integrity demanded by analytical applications. Our quality assurance includes verification of isotopic enrichment (D-atom %), chemical purity, and absence of interfering protiated species. Certificates of Analysis (COA) detailing lot-specific NMR, MS, and HPLC data are provided to ensure full traceability and compliance with your method protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material under an inert atmosphere such as argon or nitrogen to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98.0 atom % D
Chemical Purity (Protio Impurity)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.