Description

2,2-Bis(Hydroxymethyl-D2)Propionic-3,3,3-D3 Acid is a deuterated derivative of 2,2-bis(hydroxymethyl)propionic acid (bis-MPA), a key building block in dendrimer and polymer synthesis. This isotopically labeled compound is essential for advanced research and development where precise molecular tracking, metabolic studies, or enhanced spectroscopic analysis are required. It is primarily utilized by pharmaceutical researchers, material scientists, and analytical laboratories working on drug discovery, polymer kinetics, and NMR spectroscopy.

Application

• NMR Spectroscopy & Analytical Standards: Used as an internal standard or probe molecule in nuclear magnetic resonance (NMR) studies due to its deuterium labeling.
• Pharmaceutical Research: Serves as a labeled precursor in the synthesis of deuterated active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Polymer & Dendrimer Science: A critical monomer for synthesizing deuterated hyperbranched polymers and dendrimers, enabling detailed structural analysis via techniques like small-angle neutron scattering (SANS).
• Organic Synthesis Intermediate: Employed in organic chemistry to introduce a labeled, multifunctional carboxylic acid group into complex molecules.
• Mass Spectrometry: Acts as a reference compound in mass spectrometry to improve analytical accuracy and method development.
• Material Science Research: Used in the development of novel labeled coatings, resins, and biomaterials where tracking material fate and interactions is necessary.

Basic Information

Product Name	2,2-Bis(Hydroxymethyl-D2)Propionic-3,3,3-D3 Acid
CAS No.	1219802-03-5
Molecular Formula	C5D7H2O4
Molecular Weight	151.16 g/mol (deuterated form)
Synonyms	Deuterated Bis-MPA; 2,2-Bis(methanol-d2)propionic-3,3,3-d3 acid; D7-Bis-MPA; 2,2-Bis(hydroxymethyl-d2)propanoic-3,3,3-d3 acid; Perdeuterated Dimethylolpropionic Acid; Bis-MPA-d7; 2,2-Bis[(2H)hydroxymethyl]propionic-(3,3,3-2H3) acid; (2,2-Bis((2H3)methylol)propionic-3,3,3-d3 acid)
EINECS	Contact for details

Quality Control

Every batch of our deuterated chemicals is produced and analyzed under strict quality protocols. We guarantee high isotopic purity and chemical purity to meet the exacting requirements of research and development. Comprehensive testing includes assay by NMR, isotopic enrichment by MS, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuteration Degree)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.