Description

4-Hydroxypiperidine--D5 is a deuterium-labeled analog of 4-hydroxypiperidine, a versatile heterocyclic building block. This isotopically labeled compound is essential for creating internal standards and metabolites used in quantitative mass spectrometry, ensuring accurate and reliable analytical results. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in drug metabolism and pharmacokinetics (DMPK) studies.

Application

• As an internal standard for the quantification of 4-hydroxypiperidine and its derivatives in bioanalytical methods using LC-MS/MS.
• In the synthesis of deuterium-labeled drug metabolites for use as reference materials in pharmacokinetic studies.
• For mechanistic studies in medicinal chemistry, utilizing the kinetic isotope effect (KIE) to probe reaction pathways.
• As a specialized building block in the development of novel labeled compounds for research in neuroscience and other therapeutic areas.
• In quality control and method validation within pharmaceutical manufacturing to ensure assay specificity and accuracy.

Basic Information

Product Name	4-Hydroxypiperidine--D5
CAS No.	1219799-35-5
Molecular Formula	C5H4D5NO
Molecular Weight	108.17 g/mol
Synonyms	4-Hydroxypiperidine-d5; Piperidin-4-ol-d5; 1,2,3,5,6-Pentadeuterio-4-hydroxypiperidine; 4-Hydroxy-1,2,3,5,6-pentadeuteriopiperidine; Deuterated 4-Hydroxypiperidine; 4-HP-d5; 4-Hydroxypiperidine (pentadeuterated)
EINECS	Contact for details

Quality Control

Our 4-Hydroxypiperidine--D5 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic enrichment, and purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.