Description

Cyclopropyl Methyl Ketone-D8 is a deuterated analog of cyclopropyl methyl ketone, where eight hydrogen atoms are replaced with deuterium. This isotopic labeling makes it an invaluable internal standard and tracer in quantitative mass spectrometry and metabolic studies, ensuring high analytical accuracy and reliability. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for advanced research and development.

Application

• Internal standard for the quantification of cyclopropyl methyl ketone and related compounds via Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS).
• Tracer molecule in pharmacokinetic, metabolic pathway, and drug degradation studies.
• Key intermediate in the synthesis of deuterated active pharmaceutical ingredients (APIs) for clinical research.
• Essential reference material in forensic and environmental analysis for precise compound identification.
• Used in mechanistic studies and reaction monitoring in organic and medicinal chemistry research.
• Critical component in the development and validation of analytical methods requiring isotopic dilution techniques.

Basic Information

Product Name	Cyclopropyl Methyl Ketone-D8
CAS No.	1219799-33-3
Molecular Formula	C5D8O
Molecular Weight	88.16 g/mol
Synonyms	Deuterated Cyclopropyl Methyl Ketone; Perdeuterated Cyclopropyl Methyl Ketone; Cyclopropanecarbaldehyde-D8; 1-Cyclopropyl-1-deuterioethanone-D7; (Methyl-D3)(cyclopropyl-D5)ketone; Acetyl-D3-cyclopropane-D5; CPK-D8; Cyclopropyl(methyl-d3)ketone-d5
EINECS	Contact for details

Quality Control

Our Cyclopropyl Methyl Ketone-D8 is produced under stringent quality control protocols to ensure exceptional isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, GC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity, and solvent residues is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and open flame. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.