Description

2-Bromobutyric-2,3,3,4,4,4-D6 Acid CAS NO 1219799-08-2 is a deuterium-labeled derivative of 2-bromobutyric acid, serving as a critical stable isotope-labeled building block for advanced research and development. This high-purity compound is essential for creating internal standards and labeled analogs in quantitative mass spectrometry, ensuring unparalleled accuracy in analytical measurements. It is primarily utilized by pharmaceutical, agrochemical, and academic research laboratories engaged in metabolic studies, pharmacokinetics, and tracer analysis.

Application

• Internal Standard for LC/MS and GC/MS: Used as a quantitative reference standard in mass spectrometry to improve the precision and accuracy of analyte measurement in complex biological matrices.
• Metabolic Pathway Tracing: Enables the study of drug metabolism and biochemical pathways by tracking the incorporation of the deuterium label.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants during drug development.
• Synthesis of Deuterated Active Pharmaceutical Ingredients (APIs): Acts as a key synthon for the preparation of deuterium-labeled drug candidates, which can offer improved metabolic stability.
• Environmental and Food Safety Analysis: Supports accurate residue analysis of pesticides, toxins, and contaminants in environmental and food samples.
• NMR Spectroscopy Studies: The deuterium atoms provide a non-perturbing probe for mechanistic and structural studies using nuclear magnetic resonance.

Basic Information

Product Name	2-Bromobutyric-2,3,3,4,4,4-D6 Acid
CAS No.	1219799-08-2
Molecular Formula	C4H2D6BrO2
Molecular Weight	182.04 g/mol (deuterated form)
Synonyms	2-Bromo-2,3,3,4,4,4-hexadeuteriobutanoic acid; (2,3,3,4,4,4-Hexadeuterio-2-bromo)butyric Acid; Deuterated 2-Bromobutyric Acid; 2-Bromobutyric Acid-d6; α-Bromobutyric Acid-d6; Butanoic-2,3,3,4,4,4-d6 acid, 2-bromo-; 2-Bromobutanoic-2,3,3,4,4,4-d6 Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromobutyric-2,3,3,4,4,4-D6 Acid is manufactured and tested under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm deuterium incorporation and chemical identity. Certificates of Analysis (COA) detailing isotopic purity (e.g., D% or atom % D), chemical purity, and analytical methods are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as bases, oxidizing agents, and reactive metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98.0 atom % D
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.