Description

3-Chloro-N,n-Dimethyl-D6-Propylamine HCl is a deuterium-labeled analog of a key amine intermediate, offering a stable isotopic label for advanced research and development. This compound is critical for applications requiring precise metabolic and pharmacokinetic studies, where tracking molecular pathways is essential. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical developers, and academic institutions engaged in tracer studies, analytical method development, and the synthesis of labeled active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research: As a stable isotope-labeled internal standard for accurate quantification in LC-MS and GC-MS analysis of drugs and metabolites.
• Metabolic Pathway Tracing: Used in deuterium labeling studies to investigate drug metabolism, absorption, distribution, and excretion (ADME) profiles.
• Chemical Synthesis Intermediate: A building block for the synthesis of more complex deuterated compounds, including potential APIs and agrochemicals.
• Analytical Method Development: Serves as a critical reference material for validating analytical methods in compliance with regulatory guidelines (e.g., FDA, ICH).
• Mechanistic Studies: Enables the study of reaction mechanisms and isotopic effects in organic and medicinal chemistry.

Basic Information

Product Name	3-Chloro-N,n-Dimethyl-D6-Propylamine HCl
CAS No.	1219799-04-8
Molecular Formula	C5H7D6Cl2N
Molecular Weight	164.12 g/mol
Synonyms	3-Chloro-N,N-dimethylpropylamine-d6 hydrochloride; 1-Chloro-3-(dimethylamino)propane-d6 hydrochloride; N,N-Dimethyl-3-chloropropylamine-d6 hydrochloride; Deuterated 3-Chloropropyldimethylamine HCl; (3-Chloropropyl)dimethylamine-d6 hydrochloride; 3-(Dimethylamino)-1-chloropropane-d6 hydrochloride; N,N-Dimethyl-3-chloro-1-propanamine-d6 hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-N,n-Dimethyl-D6-Propylamine HCl is produced and tested under strict quality management systems to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (D-content), chemical purity, and identity confirmation. Our quality commitment aligns with the standards expected for research-grade chemicals in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.