Description

n-Suberylglycine-2,2-D2 is a deuterium-labeled derivative of suberylglycine, a key intermediate and biomarker in metabolic studies. This compound is specifically engineered to provide an internal standard for mass spectrometry, ensuring unparalleled accuracy and reproducibility in quantitative analysis. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, clinical diagnostics, and metabolomics sectors who require high-fidelity analytical standards for metabolic pathway investigation and biomarker validation.

Application

• Internal standard for the precise quantification of suberylglycine in biological matrices via LC-MS/MS and GC-MS.
• Critical reagent in metabolomics research for studying inborn errors of metabolism, particularly related to fatty acid oxidation.
• Use in the development and validation of clinical diagnostic assays for metabolic disorders.
• Biomarker research and discovery in academic and pharmaceutical R&D settings.
• Quality control and method development in reference material and analytical service laboratories.
• Stable isotope-labeled standard for pharmacokinetic and pharmacodynamic studies in drug development.

Basic Information

Product Name	n-Suberylglycine-2,2-D2
CAS No.	1219799-02-6
Molecular Formula	C₁₀H₁₆D₂NO₄⁺
Molecular Weight	218.26 g/mol (for unlabeled form, contact for exact deuterated mass)
Synonyms	Suberylglycine-2,2-d2; 8-Carboxyoctanoylglycine-2,2-d2; 2-[(1,1-Dideuterio-2-oxo-2-hydroxyethyl)amino]-8-oxooctanoic acid; Deuterated Suberylglycine; d2-Suberylglycine; Hexanedicarboxyglycine-2,2-d2; Isotope-labeled suberic acid glycine conjugate
EINECS	Contact for details

Quality Control

Our n-Suberylglycine-2,2-D2 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic purity (by MS), and residual solvent content. We adhere to relevant industry guidelines for the production of high-quality reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.