Description

4-Fluorobenzyl--D4-Amine CAS NO 1219798-96-5 is a deuterium-labeled analog of 4-fluorobenzylamine, a valuable building block in synthetic organic chemistry. This isotopically labeled compound is essential for creating internal standards used in quantitative mass spectrometry, ensuring high accuracy and reliability in analytical measurements. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries for drug metabolism studies, pharmacokinetic research, and the development of novel chemical entities.

Application

• Pharmaceutical Research & Development: Serves as a critical deuterated intermediate for synthesizing isotopically labeled drug candidates and metabolites for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Chemistry & Mass Spectrometry: Used as a high-purity internal standard for the accurate quantification of 4-fluorobenzylamine and related compounds in complex biological matrices via LC-MS/MS and GC-MS.
• Agrochemical Development: Employed in the synthesis of deuterated analogs of pesticides and herbicides for environmental fate studies and metabolic pathway tracing.
• Material Science Research: Acts as a specialized monomer or precursor for developing novel deuterated polymers and advanced materials with unique spectroscopic properties.
• Metabolomics & Biomarker Discovery: Facilitates precise tracking and quantification in metabolic flux analysis and the discovery of disease biomarkers.

Basic Information

Product Name	4-Fluorobenzyl--D4-Amine
CAS No.	1219798-96-5
Molecular Formula	C7H4D4FN
Molecular Weight	129.17 g/mol
Synonyms	4-Fluorobenzyl-d4-amine; 4-Fluoro(α,α,α',α'-d4)benzylamine; (4-Fluorophenyl-d4)methanamine; 1-(4-Fluorophenyl-d4)methanamine; Deuteron 4-Fluorobenzylamine; 4-Fluorobenzylamine-d4; 4-Fluoro-d4-benzylamine; 4-Fluorobenzylamine (phenyl-d4)
EINECS	Contact for details

Quality Control

Every batch of 4-Fluorobenzyl--D4-Amine is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, with comprehensive analysis performed using advanced techniques including NMR (¹H, ¹³C, ¹⁹F) and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity (by HPLC/GC), isotopic purity (D-enrichment), and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and moisture absorption. Allow the sealed container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.