Description

3-Methylpentanedioic--D4 Acid is a deuterated isotopologue of 3-methylglutaric acid, where four hydrogen atoms are replaced by deuterium. This isotopic labeling is critical for applications requiring non-radioactive tracing, internal standards, and metabolic studies, providing enhanced mass spectrometry signal resolution and stability. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-purity, stable-isotope labeled compounds for advanced R&D and quality control.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of endogenous metabolites or drug compounds.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and metabolomic studies to track the fate of molecules without radioactive labels.
• Pharmaceutical Intermediate: Serves as a deuterated synthon in the development of novel Active Pharmaceutical Ingredients (APIs) with improved metabolic stability.
• NMR Spectroscopy Solvent & Reagent: Utilized as a probe or shifting agent in nuclear magnetic resonance studies due to its distinct spectral properties.
• Agrochemical Research: Applied in the development and environmental fate studies of new pesticides and herbicides.
• Chemical Reference Material: Acts as a high-purity certified material for calibrating analytical instruments and validating methods.

Basic Information

Product Name	3-Methylpentanedioic--D4 Acid
CAS No.	1219798-68-1
Molecular Formula	C6H2D4O4
Molecular Weight	150.15 g/mol
Synonyms	3-Methylglutaric-d4 Acid; 3-Methylglutaric Acid-d4; (3-Methyl-1,5-pentanedioic)-d4 Acid; 3-Methylpentanedioic Acid-d4; Deuterated 3-Methylglutaric Acid; [2H4]-3-Methylglutaric Acid; 3-Methylglutaric-2,2,4,4-d4 Acid; Isotopic Labeled 3-Methylglutaric Acid
EINECS	Contact for details

Quality Control

Our 3-Methylpentanedioic--D4 Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, MS, and HPLC, to ensure high isotopic purity and chemical purity suitable for sensitive research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation and maintain isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.