Description

N‐Pentyl 4‐Hydroxybenzoate‐2,3,5,6‐D4 is a deuterated analog of n-pentyl paraben, a compound widely used as a preservative and antimicrobial agent. This deuterium-labeled version is specifically designed for use as an internal standard in quantitative analytical methods, providing unmatched accuracy and reliability in mass spectrometry and chromatography. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, food science, and cosmetic industries who require precise measurement of parabens and their metabolites. The compound's stable isotopic labeling eliminates interference, enabling superior method validation and trace analysis.

Application

• Internal Standard for Analytical Chemistry: Primary use as a quantitative reference standard in LC-MS/MS, GC-MS, and HPLC methods for analyzing parabens.
• Pharmaceutical Research & Development: Used in pharmacokinetic, metabolic stability, and bioequivalence studies to track the fate of pentyl paraben and related compounds.
• Food & Beverage Safety Testing: Enables accurate quantification of pentyl paraben preservative residues in food products and packaging materials.
• Cosmetic & Personal Care Product Analysis: Critical for compliance testing, ensuring preservative levels in lotions, creams, and other products meet regulatory limits.
• Environmental Monitoring: Assists in tracing the environmental fate and concentration of paraben esters in water and soil samples.
• Method Development & Validation: Serves as a key component in developing robust, high-precision analytical protocols for regulatory submission.

Basic Information

Product Name	N‐Pentyl 4‐Hydroxybenzoate‐2,3,5,6‐D4
CAS No.	1219798-66-9
Molecular Formula	C₁₂H₁₀D₄O₃
Molecular Weight	206.26 g/mol (approx.)
Synonyms	Pentyl Paraben-d4; 4-Hydroxybenzoic Acid Pentyl Ester-d4; n-Pentyl p-Hydroxybenzoate-d4; Benzoic acid, 4-hydroxy-, pentyl ester-2,3,5,6-d4; Deuterated Pentyl Paraben; Pentyl 4-Hydroxybenzoate-2,3,5,6-D4; [2,3,5,6-2H4]Pentyl 4-hydroxybenzoate
EINECS	Contact for details

Quality Control

Every batch of N‐Pentyl 4‐Hydroxybenzoate‐2,3,5,6‐D4 is manufactured and analyzed under strict quality systems to ensure the highest isotopic purity and chemical integrity required for analytical applications. Our quality commitment includes comprehensive characterization by NMR (¹H, ¹³C), mass spectrometry, and HPLC to confirm deuterium incorporation, chemical purity, and absence of unlabeled impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data including assay, isotopic enrichment, and chromatographic purity.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Chemical Purity (¹H NMR)	Conforms
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.