Description

3′‐Methoxyacetophenone‐2′,4′,5′,6′‐D4 is a deuterium-labeled isotopologue of 3′-Methoxyacetophenone, a key aromatic ketone building block. This compound matters for its utility as a stable internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability in complex matrices. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries for drug metabolism studies, pharmacokinetic research, and quality control of related active ingredients.

Application

• Internal Standard for LC-MS/MS: Used as a stable, non-interfering reference compound for the precise quantification of 3′-Methoxyacetophenone and its metabolites in biological and environmental samples.
• Pharmaceutical Research & Development: Critical for drug metabolism and pharmacokinetic (DMPK) studies, enabling accurate tracking of parent compounds and their breakdown pathways.
• Analytical Method Development: Serves as a calibration standard in the development and validation of sensitive analytical methods for regulatory compliance.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision analytical techniques to minimize matrix effects and improve measurement accuracy.
• Chemical Synthesis Tracing: Acts as a labeled precursor or intermediate in the synthesis of more complex deuterated molecules for mechanistic studies.
• Quality Control & Assurance: Used in-house by chemical suppliers and end-users to verify the purity and concentration of non-labeled 3′-Methoxyacetophenone batches.

Basic Information

Product Name	3′‐Methoxyacetophenone‐2′,4′,5′,6′‐D4
CAS No.	1219798-58-9
Molecular Formula	C9H6D4O2
Molecular Weight	154.21 g/mol (approx.)
Synonyms	1-(3-Methoxyphenyl)ethanone-2,4,5,6-d4; 3'-Methoxyacetophenone-d4; 3-Acetylanisole-d4; m-Methoxyacetophenone-d4; 1-(3-Methoxyphenyl)ethanone-2',4',5',6'-d4; Deuterated 3′-Methoxyacetophenone; 3-Methoxyacetophenone (phenyl-d4); Ethanone, 1-(3-methoxyphenyl)-2,4,5,6-d4-
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality protocols to ensure high isotopic purity and chemical integrity. Each batch of 3′‐Methoxyacetophenone‐2′,4′,5′,6′‐D4 is characterized by advanced analytical techniques including NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity (by HPLC), and other critical parameters is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.