Description

4-Methoxyaniline--D4 is a deuterium-labeled derivative of 4-methoxyaniline, a key aniline compound. This stable isotope-labeled analog is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily required by research and development laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for advanced metabolic, pharmacokinetic, and environmental fate studies.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of 4-methoxyaniline and its metabolites in complex biological matrices.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion of parent compounds.
• Analytical Method Development: Serves as a reference material for validating and calibrating sensitive analytical methods in contract research organizations (CROs).
• Environmental Analysis: Aids in the detection and quantification of aniline-based compounds in environmental samples for regulatory compliance testing.
• Chemical Synthesis Research: Employed as a labeled building block in the synthesis of deuterated complex molecules for mechanistic studies.

Basic Information

Product Name	4-Methoxyaniline--D4
CAS No.	1219798-55-6
Molecular Formula	C7H5D4NO
Molecular Weight	127.17 g/mol (approx.)
Synonyms	p-Anisidine-d4; 4-Aminoanisole-d4; 4-Methoxyaniline-d4; 4-Methoxybenzenamine-d4; p-Methoxyaniline-d4; Deuterated p-Anisidine; [2H4]-4-Methoxyaniline; 4-Methoxy-[2,3,5,6-2H4]aniline
EINECS	Contact for details

Quality Control

Our 4-Methoxyaniline--D4 is produced under strict quality management systems to ensure high chemical and isotopic purity, critical for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (atom % D), chemical purity by HPLC, and identity confirmation by NMR and mass spectrometry. We support research and industrial standards, including GMP where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.