Description

Hexestrol-D6 (Hexane-2,2,3,4,5,5-D6) (Meso) is a deuterated isotopologue of the synthetic estrogen hexestrol, specifically labeled on the hexane moiety. This compound is a critical tool in analytical chemistry, providing a stable internal standard for the precise quantification of hexestrol and related compounds using mass spectrometry. It is essential for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and forensic toxicology sectors who require high-fidelity analytical data. The compound is supplied with the CAS number 1219798-48-7.

Application

• Internal Standard for Mass Spectrometry (MS): Primary use as a stable, non-interfering internal standard for the accurate quantification of hexestrol in complex biological and environmental matrices via LC-MS/MS and GC-MS.
• Pharmaceutical Research & Development: Enables precise pharmacokinetic and metabolic studies of estrogenic compounds, supporting drug discovery and bioanalytical method validation.
• Clinical and Forensic Toxicology: Used in assays to detect and quantify synthetic estrogens in human and animal samples for diagnostic and legal purposes.
• Environmental Analysis: Facilitates the monitoring of endocrine-disrupting chemical residues in water, soil, and food samples with high accuracy.
• Metabolomics and Biomarker Discovery: Serves as a reference compound in studies investigating estrogen metabolism and identifying related biomarkers.
• Quality Control & Regulatory Compliance: Supports analytical method development and verification to meet stringent regulatory requirements (e.g., FDA, EMA) in pharmaceutical manufacturing.

Basic Information

Item	Detail
Product Name	Hexestrol-D6 (Hexane-2,2,3,4,5,5-D6) (Meso)
CAS No.	1219798-48-7
Molecular Formula	C18H18D6O2
Molecular Weight	274.42 g/mol
Synonyms	Hexestrol-d6; Meso-Hexestrol-d6; 4,4'-(1,2-Diethyl-3,4-dimethyl-1,2-ethanediyl)bisphenol-d6; 3,4-Bis(4-hydroxyphenyl)-2,3-diethylhexane-d6; Dihydrodiethylstilbestrol-d6; Hexanoestrol-d6; NSC-9895-d6; Isotopically Labeled Hexestrol
EINECS	Contact for details

Quality Control

Our Hexestrol-D6 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic purity (≥98% D) and chemical identity. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes batch-specific data on purity, assay, and residual solvent content. Our quality systems are designed to support GMP and ISO-guided research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (Chemical Purity)
Isotopic Purity (NMR/MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.