Description

1-Bromo-2,5-Difluorobenzene-D3 is a deuterated aromatic compound, specifically a benzene derivative where three hydrogen atoms are replaced by deuterium, serving as a stable isotope-labeled standard. This high-purity compound is essential for applications requiring precise analytical tracking and mechanistic studies, offering superior signal differentiation in spectroscopic analysis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for drug development, metabolic research, and as a key synthetic intermediate.

Application

• Pharmaceutical Research & Development: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantitative analysis of drug metabolites and pharmacokinetic studies.
• Agrochemical Synthesis: Acts as a deuterium-labeled building block in the synthesis of novel pesticides and herbicides, enabling the study of environmental fate and degradation pathways.
• Organic Synthesis Intermediate: Serves as a versatile precursor for synthesizing more complex deuterated compounds, leveraging the bromine atom for further functionalization via cross-coupling reactions.
• NMR Spectroscopy: Provides a non-interfering spectroscopic tracer in Nuclear Magnetic Resonance (NMR) experiments for reaction monitoring and structural elucidation.
• Material Science: Employed in the development of specialty polymers and liquid crystals where isotopic labeling is used to study molecular dynamics and ordering.

Basic Information

Product Name	1-Bromo-2,5-Difluorobenzene-D3
CAS No.	1219795-54-6
Molecular Formula	C6H2D3BrF2
Molecular Weight	195.99 g/mol (approx.)
Synonyms	2,5-Difluorobromobenzene-D3; Benzene-D3, 1-bromo-2,5-difluoro-; 1-Bromo-2,5-difluorobenzene (phenyl-D3); 2,5-Difluoro-1-bromobenzene-D3; Deutero-1-Bromo-2,5-Difluorobenzene; [2H3]-1-Bromo-2,5-difluorobenzene; Bromo-2,5-difluorobenzene-d3; 1-Bromo-2,5-difluorobenzene (ring-D3)
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,5-Difluorobenzene-D3 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC-MS, and HPLC, to ensure high chemical purity and isotopic enrichment. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and impurity profiles is provided with every shipment to guarantee consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.