Description

4-Tolyl-D4-Sulfonamide is a high-purity, deuterated chemical building block of significant importance in advanced research and development. Its core value lies in its use as a stable isotope-labeled internal standard, which is critical for ensuring accuracy and reliability in quantitative analytical methods. This compound is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise measurement and metabolic studies.

Application

• As a deuterated internal standard for the precise quantification of sulfonamide analogs in complex matrices using LC-MS/MS and GC-MS.
• In pharmaceutical research for drug metabolism and pharmacokinetics (DMPK) studies, enabling accurate tracking of compound distribution and clearance.
• For the synthesis of labeled reference materials and metabolites used in regulatory bioanalysis and clinical trials.
• In academic and industrial R&D involving mechanistic studies, reaction pathway elucidation, and isotope effect investigations.
• As a specialized reagent in the development of diagnostic assays and analytical methods requiring high specificity and sensitivity.

Basic Information

Product Name	4-Tolyl-D4-Sulfonamide
CAS No.	1219795-34-2
Molecular Formula	C7H4D4NO2S
Molecular Weight	174.23 g/mol
Synonyms	p-Tolyl-d4-sulfonamide; 4-Methyl-d4-benzenesulfonamide; Deutero-p-toluenesulfonamide; Benzenesulfonamide, 4-methyl-d4-; Toluene-d4-4-sulfonamide; 4-(Methyl-d4)benzenesulfonamide; p-Toluenesulfonamide-d4
EINECS	Contact for details

Quality Control

Every batch of 4-Tolyl-D4-Sulfonamide is produced and tested under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic analyses, to ensure compliance with the stringent requirements for isotope-labeled compounds. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.