Description

4,4'-Methylenedianiline--D8 is a deuterated analog of 4,4'-methylenedianiline (MDA), a key aromatic amine. This isotopically labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily required by analytical laboratories, pharmaceutical researchers, and chemical manufacturers engaged in trace analysis, method development, and quality control for materials like polyurethanes and epoxy resins.

Application

• Internal Standard for Mass Spectrometry (MS): Critical for the precise quantification of 4,4'-MDA and related compounds in LC-MS/MS and GC-MS analyses.
• Pharmaceutical Research & Metabolism Studies: Used in pharmacokinetic and metabolic pathway studies to track and quantify drug metabolites.
• Polymer & Industrial Chemical Analysis: Enables accurate measurement of residual or hydrolyzed MDA monomers in polyurethane foams, epoxy resins, and other industrial products.
• Environmental and Occupational Safety Testing: Supports monitoring programs for MDA exposure in workplace air, water, and biological samples.
• Regulatory Compliance & Method Validation: Facilitates method development and validation to meet stringent regulatory requirements from agencies like the EPA and FDA.
• Deuterated Reference Material Synthesis: Serves as a building block for synthesizing other deuterated compounds for research and analytical purposes.

Basic Information

Product Name	4,4'-Methylenedianiline--D8
CAS No.	1219795-26-2
Molecular Formula	C13H2D8N2
Molecular Weight	204.31 g/mol
Synonyms	4,4'-Methylenebis(aniline)-d8; Bis(4-aminophenyl)methane-d8; MDA-d8; 4,4'-Diaminodiphenylmethane-d8; Deuterated 4,4'-MDA; 4,4'-Methylenedianiline (phenyl-d8); p,p'-Methylenedianiline-d8; D8-4,4'-MDA
EINECS	Contact for details

Quality Control

Our 4,4'-Methylenedianiline--D8 is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, essential for its role as a reference material. Each batch is characterized by advanced analytical techniques including NMR and mass spectrometry to confirm deuterium incorporation and purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.