Description

2-Bromo-2-Methyl-D3-Propionic-3,3,3-D3 Acid CAS NO 1219795-23-9 is a high-purity, deuterium-labeled analog of 2-bromo-2-methylpropionic acid, serving as a critical stable isotope-labeled building block. This compound is essential for advanced research and development where precise molecular tracking and metabolic studies are required. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and analytical scientists working in drug discovery, metabolic pathway analysis, and the synthesis of isotopically labeled compounds.

Application

• Pharmaceutical Research & Development: As a deuterium-labeled intermediate in the synthesis of isotopically labeled Active Pharmaceutical Ingredients (APIs) for pharmacokinetic, metabolic stability (deuterium swap), and mass spectrometry studies.
• Agrochemical Development: Used in creating labeled analogs of herbicides or plant growth regulators to study environmental fate, degradation pathways, and residue analysis.
• Analytical Chemistry & Mass Spectrometry: Serves as an internal standard or reference material in quantitative LC-MS/MS and GC-MS methods, enhancing accuracy in bioanalytical assays.
• Organic Synthesis & Medicinal Chemistry: A versatile building block for introducing the 2-bromo-2-methylpropionyl moiety in deuterated form, enabling structure-activity relationship (SAR) studies and novel compound libraries.
• Metabolic Pathway Tracing: Employed in biochemical research to trace and elucidate specific metabolic pathways using stable isotope labeling techniques.
• Material Science Research: Potential use in the synthesis of specialized, labeled polymers or coatings for research into material properties and degradation.

Basic Information

Product Name	2-Bromo-2-Methyl-D3-Propionic-3,3,3-D3 Acid
CAS No.	1219795-23-9
Molecular Formula	C4D6BrO2
Molecular Weight	169.00 g/mol (for deuterated form)
Synonyms	2-Bromo-2-methylpropionic-3,3,3-d3 acid-d3; (D3)-2-Bromo-2-methylpropanoic-3,3,3-d3 acid; 2-Bromo-2-(methyl-d3)propionic-3,3,3-d3 acid; α-Bromoisobutyric-d6 acid; Deuterated α-Bromoisobutyric Acid; Hexadeutero-2-bromo-2-methylpropionic acid; Perdeutero 2-bromoisobutyric acid; BIBM-d6
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-Methyl-D3-Propionic-3,3,3-D3 Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, isotopic enrichment, and consistency. Standard specifications are verified by NMR (1H, 13C), mass spectrometry, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its nature as a strong acid/organic solvent, handle with appropriate precautions in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.