Description

p-Toluene-D7-Sulfonic Acid H2O is a deuterated isotopologue of p-toluenesulfonic acid monohydrate, where seven hydrogen atoms are replaced by deuterium, offering a high isotopic purity for advanced research and analytical applications. This compound serves as a critical labeled reagent and internal standard in mass spectrometry and NMR spectroscopy, enabling precise quantification and mechanistic studies in complex chemical and biological systems. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and material science who require stable, non-radioactive isotopic tracers for kinetic studies, metabolic pathway analysis, and method validation.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analyses for pharmaceuticals and metabolites.
• NMR Spectroscopy Solvent & Reagent: Employed as a deuterated acid catalyst or shift reagent in nuclear magnetic resonance studies to avoid proton interference.
• Pharmaceutical Research & Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies by tracing reaction pathways and degradation products.
• Mechanistic Organic Chemistry Studies: Acts as a labeled acid catalyst to investigate reaction mechanisms, kinetics, and isotopic effects.
• Agrochemical Analysis: Serves as a standard in the environmental and residue analysis of pesticides and herbicides.
• Material Science Research: Used in the synthesis and analysis of deuterated polymers and advanced organic materials.

Basic Information

Product Name	p-Toluene-D7-Sulfonic Acid H2O
CAS No.	1219795-22-8
Molecular Formula	C7D7SO3·H2O
Molecular Weight	195.26 g/mol (anhydrous basis)
Synonyms	4-Methyl-D7-benzenesulfonic Acid Monohydrate; Deuterated p-Toluenesulfonic Acid Monohydrate; p-Toluenesulfonic Acid-d7 Monohydrate; p-TSA-d7·H2O; 4-(Trideuteriomethyl)benzenesulfonic Acid-d4 Monohydrate; Tosic Acid-d7 Monohydrate; PTsOH-d7·H2O
EINECS	Contact for details

Quality Control

Every batch of p-Toluene-D7-Sulfonic Acid H2O is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure it meets the high-purity requirements for research and analytical applications. Certificates of Analysis (COA) detailing isotopic purity (D-enrichment), chemical purity (by HPLC/NMR), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	4.0 - 6.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.