Description

N,n-Dimethyl-D3-Glycine Hcl (n-Methyl-D3) is a deuterium-labeled derivative of dimethylglycine hydrochloride, a compound of significant interest in advanced research and development. This stable isotope-labeled analog is essential for applications requiring precise metabolic and pharmacokinetic tracing, offering enhanced analytical sensitivity and specificity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for use as an internal standard, tracer, or building block in the synthesis of labeled compounds.

Application

• As a stable isotope-labeled internal standard for the accurate quantification of dimethylglycine and related metabolites in bioanalytical methods like LC-MS/MS.
• Use in pharmaceutical research and drug development for conducting metabolism studies (ADME) and pharmacokinetic profiling.
• As a key precursor or building block in the synthesis of more complex deuterium-labeled compounds for research purposes.
• Application in nutritional and biomedical research to investigate choline metabolism, methylation cycles, and related biochemical pathways.
• Employed in diagnostic assay development to enhance the precision and reliability of clinical tests.

Basic Information

Product Name	N,n-Dimethyl-D3-Glycine Hcl (n-Methyl-D3)
CAS No.	1219795-14-8
Molecular Formula	C4H6D3ClNO2
Molecular Weight	138.57 g/mol (approx.)
Synonyms	Dimethyl-d3-glycine hydrochloride; (Dimethylamino-d3)acetic acid hydrochloride; N,N-Dimethyl-d3-glycine HCl; N-Methyl-d3-glycine hydrochloride; Deuterated dimethylglycine HCl; DMG-d3 hydrochloride; (Carboxymethyl)dimethyl-d3-ammonium chloride; 2-(Dimethyl-d3-amino)acetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-D3-Glycine Hcl is produced under strict quality management protocols to ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and identity are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.