Description

Butyric-d4 Acid is a deuterium-labeled isotopologue of butyric acid, where four hydrogen atoms are replaced by deuterium. This high-purity stable isotope-labeled compound is essential for advanced analytical and research applications requiring precise molecular tracking. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and metabolic research sectors for use as an internal standard in mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Provides accurate quantification in GC-MS and LC-MS analyses of short-chain fatty acids and related metabolites.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent or a non-interfering tracer in complex reaction and metabolic pathway studies.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to trace the fate of butyrate and its derivatives.
• Nutritional & Microbiome Research: Enables precise tracking of butyrate production and absorption in gut microbiome and metabolic health studies.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex deuterated compounds.
• Quality Control & Method Development: Critical for developing and validating robust analytical methods in regulatory environments.

Basic Information

Product Name	Butyric-d4 Acid
CAS No.	1219794-99-6
Molecular Formula	C4D4H4O2 or C4H4D4O2
Molecular Weight	92.12 g/mol
Synonyms	Butanoic-d4 acid; Deuterated Butyric Acid; [2,2,3,3-2H4]Butyric Acid; Tetradeutero-butanoic acid; Butyric Acid-d4; n-Butyric-d4 Acid; 1-Propane carboxylic-2,2,3,3-d4 acid; Butyric Acid (D4)
EINECS	Contact for details

Quality Control

Every batch of Butyric-d4 Acid is manufactured and tested under strict quality systems to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity by NMR and HPLC, and impurity profiles. Our quality commitment aligns with the standards expected for research chemicals and analytical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98.0 atom % D
Chemical Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.