Description

1-Butane-D9-Sulfonyl Chloride is a high-purity, deuterium-labeled derivative of butanesulfonyl chloride, a versatile reagent in synthetic chemistry. Its primary value lies in its use as a stable isotope-labeled intermediate, enabling precise tracking and quantification in analytical and metabolic studies. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require deuterated building blocks for the development of new compounds, active pharmaceutical ingredients (APIs), and analytical standards.

Application

• Deuterated Pharmaceutical Intermediate: A critical building block for synthesizing deuterium-labeled drug candidates and active pharmaceutical ingredients (APIs) to study metabolism, pharmacokinetics, and bioavailability.
• Metabolic Research & Tracing: Used as a stable isotope tracer in mass spectrometry and NMR-based studies to elucidate metabolic pathways and mechanisms of action.
• Analytical Standard Development: Serves as a primary standard or reference material for quantitative analysis in environmental, forensic, and clinical testing laboratories.
• Agrochemical Research: Employed in the synthesis of novel, labeled pesticides and herbicides to investigate environmental fate, degradation, and residue analysis.
• Material Science: Acts as a precursor for introducing deuterium labels into polymers or specialty chemicals to study structure-property relationships and dynamics.
• Sulfonylation Reactions: Functions as a sulfonylating agent in organic synthesis to introduce the butanesulfonyl group into target molecules, with the deuterium label providing an analytical handle.

Basic Information

Product Name	1-Butane-D9-Sulfonyl Chloride
CAS No.	1219794-70-3
Molecular Formula	C4D9ClO2S
Molecular Weight	177.70 g/mol (for C4D935ClO2S)
Synonyms	Butane-D9-sulfonyl chloride; Perdeuterobutanesulfonyl chloride; n-Butanesulfonyl-D9 chloride; 1,1,1,2,2,3,3,4,4-Nonadeuteriobutane-1-sulfonyl chloride; Deuterated butanesulfonyl chloride; D9-Butanesulfonyl chloride; Butane-1-sulfonyl-D9 chloride
EINECS	Contact for details

Quality Control

Our 1-Butane-D9-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, meeting the stringent requirements of research and development. Each batch is analyzed using advanced techniques including NMR, GC-MS, and HPLC to confirm deuterium incorporation, chemical purity, and identity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.