Description

4-Chlorobenzamide--D4 is a deuterium-labeled analog of 4-chlorobenzamide, a key chemical building block. This isotopically labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and reproducibility in analytical methods. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing industries for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of 4-chlorobenzamide and related compounds in complex biological matrices like plasma, urine, and tissue samples.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion (ADME) of parent drug molecules.
• Metabolite Identification: Aids in the structural elucidation and confirmation of drug metabolites during the development of new active pharmaceutical ingredients (APIs).
• Environmental Analysis: Employed in the detection and measurement of chlorobenzamide herbicide residues or their degradation products in water and soil samples.
• Forensic Toxicology: Supports accurate analysis in forensic investigations where quantification of specific benzamide derivatives is required.
• Method Validation: Serves as a reliable reference material to validate and comply with Good Laboratory Practice (GLP) and regulatory guidelines for analytical procedures.

Basic Information

Product Name	4-Chlorobenzamide--D4
CAS No.	1219794-65-6
Molecular Formula	C7H2D4ClNO
Molecular Weight	158.60 g/mol (deuterated form)
Synonyms	4-Chlorobenzamide-d4; Benzamide-d4, 4-chloro-; p-Chlorobenzamide-d4; 4-Chloro-benzamide-d4; Deuterated 4-Chlorobenzamide; 4-CBA-d4; [2H4]-4-Chlorobenzamide; 1219794-65-6
EINECS	Contact for details

Quality Control

Every batch of 4-Chlorobenzamide--D4 is produced and tested under stringent quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR (1H, 13C) and mass spectrometry to confirm deuteration level and structural integrity. Certificates of Analysis (COA) detailing batch-specific results for identity, purity, and isotopic enrichment are provided and traceable to in-house reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity (Deuteration)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.