Description

Sodium 6-Hydroxyhexanoate-3,3,4,4,5,5-D6 is a high-purity, deuterium-labeled derivative of 6-hydroxyhexanoic acid, a key intermediate in organic synthesis and metabolic research. This compound is essential for applications requiring precise isotopic labeling, such as internal standards for mass spectrometry and tracer studies in pharmacokinetics and metabolic pathway analysis. It is primarily utilized by pharmaceutical R&D laboratories, analytical service providers, and manufacturers of advanced diagnostic reagents.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, isotopically labeled internal standard for the accurate quantification of 6-hydroxyhexanoic acid and related metabolites in complex biological matrices like plasma, urine, and tissue homogenates.
• Metabolic Pathway Tracing: Used as a stable isotope tracer in biomedical research to elucidate the metabolic fate, distribution, and pharmacokinetics of caprolactam precursors and fatty acid oxidation products.
• Pharmaceutical Impurity Profiling: Employed in the development and validation of analytical methods for identifying and quantifying process-related impurities and degradants in active pharmaceutical ingredients (APIs).
• Synthetic Intermediate: Acts as a specialized building block for the synthesis of deuterium-labeled polymers, specialty chemicals, and novel compounds where isotopic labeling is required for study.
• Reference Material: Provides a certified reference material for calibrating analytical instruments and ensuring method accuracy in quality control laboratories.

Basic Information

Product Name	Sodium 6-Hydroxyhexanoate-3,3,4,4,5,5-D6
CAS No.	1219794-58-7
Molecular Formula	C6H5D6NaO3
Molecular Weight	164.17 g/mol (for labeled form)
Synonyms	Sodium 6-Hydroxycaproate-d6; 6-Hydroxyhexanoic-3,3,4,4,5,5-d6 Acid Sodium Salt; Sodium 6-Hydroxyhexanoate-d6; 3,3,4,4,5,5-Hexadeutero-6-hydroxyhexanoic Acid Sodium Salt; Sodium (6-Hydroxy[3,3,4,4,5,5-2H6]hexanoate); Caproic Acid, 6-Hydroxy-, Sodium Salt, d6; Sodium 6-Hydroxy-D6-hexanoate
EINECS	Contact for details

Quality Control

Our Sodium 6-Hydroxyhexanoate-3,3,4,4,5,5-D6 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (Atom % D), chemical purity (by HPLC), and identity confirmation. We adhere to relevant guidelines for the production of stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by 1H-NMR or MS)
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.