Description

Pentanedioic-D6 Anhydride is a deuterated derivative of glutaric anhydride, where six hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This high-purity labeled compound is essential for applications requiring precise molecular tracking and analysis, offering superior signal resolution in spectroscopic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a synthetic intermediate, or a tracer in metabolic and pharmacokinetic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used in quantitative LC-MS and GC-MS analysis due to its nearly identical chemical properties but distinct mass, ensuring accurate measurement of glutaric acid or related metabolites.
• Deuterated Synthetic Intermediate: Serves as a key building block for the synthesis of deuterium-labeled pharmaceuticals, agrochemicals, and other fine chemicals, enabling drug metabolism and stability studies.
• NMR Spectroscopy Tracer: Employed in Nuclear Magnetic Resonance (NMR) spectroscopy to investigate reaction mechanisms, molecular structures, and dynamics without signal interference from protonated species.
• Metabolic Pathway Research: Acts as a stable isotope tracer to elucidate biochemical pathways and the fate of glutaric acid derivatives in biological systems.
• Polymer Science Research: Used in the development and analysis of specialized polymers where deuterium labeling helps in studying polymer kinetics, morphology, and degradation.
• Quality Control & Method Development: Critical for developing and validating analytical methods in regulatory environments, ensuring method robustness and compliance.

Basic Information

Product Name	Pentanedioic-D6 Anhydride
CAS No.	1219794-53-2
Molecular Formula	C5D6O3
Molecular Weight	132.14 g/mol
Synonyms	Glutaric-D6 Anhydride; Deuterated Glutaric Anhydride; Pentanedioic Acid-d6 Anhydride; [2H6]-Glutaric Anhydride; 1,5-Pentanedioic-d6 Acid Anhydride; 3,3,4,4,5,5-Hexadeuteriodihydro-2H-pyran-2,6(3H)-dione; D6-Glutaric Anhydride
EINECS	Contact for details

Quality Control

Our Pentanedioic-D6 Anhydride is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity, isotopic enrichment (D-atom %), and impurity profiles. We adhere to relevant industry standards for fine chemicals and stable isotope-labeled compounds. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.