Description

6-Chloro-5-Iodo-2-(Methylthio)-1H-Benzimidazole is a high-purity, multi-halogenated benzimidazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical synthetic intermediate, valued for its unique halogenated structure which enables precise molecular modifications. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel heterocyclic compounds, active pharmaceutical ingredients (APIs), and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzimidazole-based drug candidates, particularly for antiviral, anticancer, and anti-parasitic applications.
• Agrochemical Research: Used in the development of new fungicides and herbicides, leveraging its halogenated benzimidazole core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and ligands in catalytic systems due to its electron-rich heterocyclic structure.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to introduce complex functionalities.
• Biochemical Tool Compound: Utilized in life science research as a probe or inhibitor to study specific enzymatic pathways and biological mechanisms.

Basic Information

Product Name	6-Chloro-5-Iodo-2-(Methylthio)-1H-Benzimidazole
CAS No.	1219741-22-6
Molecular Formula	C8H6ClIN2S
Molecular Weight	324.57 g/mol
Synonyms	6-Chloro-5-iodo-2-methylsulfanyl-1H-benzimidazole; 2-(Methylthio)-6-chloro-5-iodobenzimidazole; 1H-Benzimidazole, 6-chloro-5-iodo-2-(methylthio)-; 6-Chloro-5-iodo-2-(methylmercapto)benzimidazole; 6-Chloro-5-iodo-2-(methylsulfanyl)-1H-benzimidazole; 6-Chloro-5-iodo-2-(methylthio)benzimidazole
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Iodo-2-(Methylthio)-1H-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.