Description

5-Acetylthiophene-3-Boronic Acid Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a versatile intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by facilitating the creation of complex heterocyclic structures.
• Material Science & OLED Development: Serves as a precursor for synthesizing organic semiconductors, conductive polymers, and light-emitting materials for electronic devices.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Development: Utilized to create molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in academic and contract research organizations (CROs).

Basic Information

Product Name	5-Acetylthiophene-3-Boronic Acid Pinacol Ester
CAS No.	1219628-58-6
Molecular Formula	C₁₄H₁₉BO₃S
Molecular Weight	278.18 g/mol
Synonyms	5-Acetylthiophene-3-boronic acid pinacol ester; (5-Acetylthiophen-3-yl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-acetylthiophene; 5-Acetyl-3-thienylboronic acid pinacol ester; 5-Acetyl-3-thiopheneboronic acid pinacol ester; Pinacol (5-acetylthiophen-3-yl)boronate; 5-Acetylthiophene-3-boronic acid, pinacol cyclic ester
EINECS	Contact for details

Quality Control

Our 5-Acetylthiophene-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full characterization data are provided for every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.