Description

Bis(2-Isopropoxyphenyl)Chlorophosphine is a specialized organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile ligand precursor and reactive intermediate for constructing complex molecular architectures. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Catalyst Ligand Synthesis: Used to prepare sophisticated phosphine ligands for transition metal catalysis, enabling more efficient and selective cross-coupling reactions.
• Agrochemical Development: Serves as a building block for creating new-generation herbicides, fungicides, and plant growth regulators with improved efficacy.
• Polymer & Materials Science: Employed in the development of flame retardants, stabilizers, and specialty polymers with tailored properties.
• Organic Synthesis Reagent: Functions as a phosphorylating or chlorinating agent in multi-step synthetic routes for complex organic molecules.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new reaction methodologies and creating novel chemical entities.

Basic Information

Product Name	Bis(2-Isopropoxyphenyl)Chlorophosphine
CAS No.	1219589-19-1
Molecular Formula	C18H22ClO2P
Molecular Weight	336.79 g/mol
Synonyms	Chlorobis(2-isopropoxyphenyl)phosphine; Bis(2-isopropoxyphenyl)phosphinous chloride; 2,2'-Isopropoxy Phenyl Chlorophosphine; Phosphinous chloride, P,P-bis(2-isopropoxyphenyl)-; (2-Isopropoxyphenyl)chlorophosphine dimer; Chloro-di(2-isopropoxyphenyl)phosphine
EINECS	Contact for details

Quality Control

Our Bis(2-Isopropoxyphenyl)Chlorophosphine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.