Description

n-{[2-(2-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Glycylglycine is a specialized synthetic organic compound featuring a unique molecular architecture combining a chlorophenyl-substituted thiazole core with a glycylglycine dipeptide linker. This structure makes it a valuable high-purity building block and key intermediate in advanced chemical synthesis. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the discovery and optimization of novel bioactive molecules, particularly for applications in medicinal chemistry and proteomics research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening (HTS) for drug discovery.
• Protease Inhibitor Development: The glycylglycine moiety makes it relevant for research into inhibitors of dipeptidyl peptidases and other proteolytic enzymes.
• Bioconjugation & Chemical Biology: Acts as a linker or spacer molecule in the design of chemical probes, affinity labels, or targeted drug conjugates.
• Peptidomimetic Synthesis: Used to create peptide analogs and mimetics with enhanced stability or bioavailability for therapeutic applications.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	n-{[2-(2-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Glycylglycine
CAS No.	1219557-17-1
Molecular Formula	C14H14ClN3O3S
Molecular Weight	339.79 g/mol
Synonyms	Glycylglycine, N-[(2-(2-chlorophenyl)-4-methyl-5-thiazolyl)carbonyl]-; 2-[[2-(2-Chlorophenyl)-4-methyl-1,3-thiazole-5-carbonyl]amino]acetic acid; N-[(2-(2-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl)carbonyl]glycylglycine; (2-(2-Chlorophenyl)-4-methylthiazole-5-carbonyl)-Gly-Gly-OH; CAS 1219557-17-1
EINECS	Contact for details

Quality Control

Our n-{[2-(2-Chlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Glycylglycine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.