Description

2-(5-Methoxy-1H-Indol-1-Yl)-n-[(2E)-5-(2-Methylpropyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a unique molecular scaffold that combines indole and thiadiazole pharmacophores. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates with potential biological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• API Development: Serves as a precursor in the development of new active pharmaceutical ingredients, particularly in oncology and CNS research.
• Biochemical Research: Employed as a tool compound for studying enzyme inhibition and receptor binding assays.
• Custom Synthesis: Basis for the contract manufacturing of specialized, non-commercial chemical entities for client-specific projects.

Basic Information

Product Name	2-(5-Methoxy-1H-Indol-1-Yl)-n-[(2E)-5-(2-Methylpropyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide
CAS No.	1219554-73-0
Molecular Formula	C₁₇H₂₀N₄O₂S
Molecular Weight	344.43 g/mol
Synonyms	2-(5-Methoxy-1H-indol-1-yl)-N-[(2E)-5-(2-methylpropyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; 2-(5-Methoxyindol-1-yl)-N-[(2E)-5-isobutyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; (2E)-2-(5-Methoxy-1H-indol-1-yl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; Acetamide, 2-(5-methoxy-1H-indol-1-yl)-N-[(2E)-5-(2-methylpropyl)-1,3,4-thiadiazol-2(3H)-ylidene]-; CAS 1219554-73-0
EINECS	Contact for details

Quality Control

Our 2-(5-Methoxy-1H-Indol-1-Yl)-n-[(2E)-5-(2-Methylpropyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and pharmaceutical intermediate standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.