Description

1-{[2-(2,6-Dichlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block for medicinal chemistry research and development, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers focused on developing new drug candidates, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CROs and CMOs for custom synthesis and scale-up projects under cGMP conditions.
• Protease Inhibitor Development: Potential application in the synthesis of compounds targeting protease enzymes, given its structural motifs.
• Kinase Inhibitor Research: Serves as a valuable intermediate in the synthesis of kinase inhibitor candidates for oncology and inflammatory diseases.
• Chemical Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-{[2-(2,6-Dichlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Piperidine-3-Carboxylic Acid
CAS No.	1219553-69-1
Molecular Formula	C17H16Cl2N2O3S
Molecular Weight	399.29 g/mol
Synonyms	1-[(2-(2,6-Dichlorophenyl)-4-methyl-1,3-thiazol-5-yl)carbonyl]piperidine-3-carboxylic acid; 1-{[2-(2,6-Dichlorophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[[2-(2,6-dichlorophenyl)-4-methyl-5-thiazolyl]carbonyl]-; UNII-5J4Q8N66P8; 5J4Q8N66P8; 1219553-69-1; 1-({2-(2,6-Dichlorophenyl)-4-methyl-1,3-thiazol-5-yl}carbonyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-{[2-(2,6-Dichlorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment. We can support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.