Description

1-Methyl-n-[(2E)-5-Methyl-1,3,4-Thiadiazol-2(3H)-Ylidene]-1H-Indole-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining indole and thiadiazole moieties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting specific enzymatic pathways. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists for its role as a key building block in creating new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of new-generation pesticides and herbicides due to its bioactive heterocyclic framework.
• Biochemical Probe Synthesis: Utilized to create specialized probes and inhibitors for studying enzyme function and cellular signaling pathways.
• Material Science: Investigated as a monomer or component in the development of organic electronic materials and specialty polymers.

Basic Information

Product Name	1-Methyl-n-[(2E)-5-Methyl-1,3,4-Thiadiazol-2(3H)-Ylidene]-1H-Indole-5-Carboxamide
CAS No.	1219548-55-6
Molecular Formula	C₁₄H₁₂N₄OS
Molecular Weight	284.34 g/mol
Synonyms	1-Methyl-N-[(2E)-5-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-1H-indole-5-carboxamide; (2E)-1-Methyl-N-(5-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-1H-indole-5-carboxamide; 1-Methyl-1H-indole-5-carboxylic acid (2E)-5-methyl-1,3,4-thiadiazol-2(3H)-ylideneamide; CAS 1219548-55-6
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-n-[(2E)-5-Methyl-1,3,4-Thiadiazol-2(3H)-Ylidene]-1H-Indole-5-Carboxamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.