Description

2-(6-Bromo-1H-Indol-1-Yl)-n-[(2E)-5-(Methoxymethyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is valued for its unique molecular architecture, combining indole and 1,3,4-thiadiazole pharmacophores, which makes it a critical building block in modern medicinal chemistry. It is primarily sought by pharmaceutical researchers and fine chemical manufacturers for the synthesis of novel bioactive molecules targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new drug candidates, particularly in oncology and CNS disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme inhibition and receptor binding.
• Fine Chemical Synthesis: A versatile building block for constructing complex heterocyclic compounds in custom synthesis projects.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for client-specific synthesis programs under cGMP or research-grade conditions.

Basic Information

Product Name	2-(6-Bromo-1H-Indol-1-Yl)-n-[(2E)-5-(Methoxymethyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide
CAS No.	1219539-33-9
Molecular Formula	C₁₄H₁₃BrN₄O₂S
Molecular Weight	381.25 g/mol
Synonyms	2-(6-Bromo-1H-indol-1-yl)-N-[(2E)-5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; 2-(6-Bromoindol-1-yl)-N-[(E)-5-(methoxymethyl)-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide; (2E)-2-(6-Bromo-1H-indol-1-yl)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; Acetamide, 2-(6-bromo-1H-indol-1-yl)-N-[(2E)-5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]-; 1219539-33-9
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-1H-Indol-1-Yl)-n-[(2E)-5-(Methoxymethyl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects with research-grade material and can scale production under cGMP guidelines for advanced clinical phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.