Description

Boc-Dl-6-Methoxy-1,2,3,4-Tetrahydronorharman-1-Carboxylic Acid CAS NO 1219423-55-8 is a protected amino acid derivative featuring a complex tetracyclic β-carboline core structure. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel bioactive molecules, including potential central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloids and β-carboline-based drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Peptidomimetics Development: The Boc-protected carboxylic acid functionality allows for its incorporation into peptide chains to create novel peptidomimetic compounds.
• Chemical Biology Probes: Serves as a core structure for developing fluorescent or affinity probes to study biological pathways and protein interactions.
• Academic Research: Employed in synthetic organic chemistry for methodological development and the total synthesis of natural products.

Basic Information

Item	Detail
Product Name	Boc-Dl-6-Methoxy-1,2,3,4-Tetrahydronorharman-1-Carboxylic Acid
CAS No.	1219423-55-8
Molecular Formula	C19H24N2O5
Molecular Weight	360.41 g/mol
Synonyms	1,1-Dimethylethyl 6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-1-carboxylate; tert-Butyl 6-methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-1-carboxylate; Boc-6-MeO-THN-1-COOH; DL-6-Methoxy-1,2,3,4-tetrahydro-β-carboline-1-carboxylic acid tert-butyl ester; (R,S)-Boc-6-Methoxy-1,2,3,4-tetrahydronorharman-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Boc-Dl-6-Methoxy-1,2,3,4-Tetrahydronorharman-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.