Description

Dl-Carnitine-D9 Hcl (Trimethyl-D9) is a high-purity, isotopically labeled internal standard essential for precise quantitative analysis in advanced research and development. This deuterated compound, with CAS number 1219386-75-0, provides unmatched accuracy and reliability in mass spectrometry-based assays by eliminating interference from endogenous carnitine. It is a critical tool for pharmaceutical, clinical research, and metabolomics laboratories requiring definitive quantification of L-carnitine and its derivatives in complex biological matrices.

Application

• Quantitative Bioanalysis: Serves as a stable isotope-labeled internal standard for the accurate LC-MS/MS quantification of L-carnitine in plasma, serum, urine, and tissue samples.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion in clinical trials for carnitine-based therapeutics.
• Metabolomics & Biomarker Discovery: Used in high-throughput profiling to identify and validate carnitine-related metabolic pathways and disease biomarkers.
• Diagnostic Assay Development: Critical for calibrating and validating in-vitro diagnostic (IVD) kits and assays for conditions like primary carnitine deficiency.
• Drug Metabolism Research: Facilitates studies on the metabolic fate of carnitine and acyl-carnitines in drug development programs.
• Quality Control & Method Validation: Employed in GLP/GMP environments to validate analytical methods, ensuring regulatory compliance for pharmaceutical quality control.

Basic Information

Product Name	Dl-Carnitine-D9 Hcl (Trimethyl-D9)
CAS No.	1219386-75-0
Molecular Formula	C7H8D9ClNO3
Molecular Weight	Approx. 201.7 g/mol (Contact for exact details)
Synonyms	(±)-Carnitine-d9 hydrochloride; DL-Carnitine-d9 (trimethyl-d9) hydrochloride; 3-Carboxy-2-hydroxy-N,N,N-trimethyl-d9-propanaminium chloride; Carnitine-d9 HCl; Deuterated DL-Carnitine HCl; Internal Standard for L-Carnitine; Isotope Labeled Carnitine; Trimethyl-d9-ammonium-3-carboxy-2-hydroxypropyl chloride
EINECS	Contact for details

Quality Control

Every batch of Dl-Carnitine-D9 Hcl (Trimethyl-D9) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with the high-purity standards required for analytical and research applications. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and analytical results are provided with each shipment to guarantee traceability and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.