Description

n-Methyl-2,3-Dihydro-1H-Indole-2-Carboxamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound matters as a critical building block in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology fields. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a building block for constructing more complex indole-based heterocyclic compounds in academic and industrial research.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Biochemical Research: Utilized in the study of enzyme inhibitors and receptor ligands due to its specific molecular framework.

Basic Information

Product Name	n-Methyl-2,3-Dihydro-1H-Indole-2-Carboxamide Hydrochloride
CAS No.	1219363-16-2
Molecular Formula	C11H15ClN2O
Molecular Weight	226.70 g/mol
Synonyms	1-Methyl-2,3-dihydroindole-2-carboxamide hydrochloride; 2-Carbamoyl-1-methylindoline hydrochloride; 1-Methylindoline-2-carboxamide hydrochloride; N-Methylindoline-2-carboxamide HCl; 1-Methyl-2,3-dihydro-1H-indole-2-carboxylic acid amide hydrochloride; 1219363-16-2; 2,3-Dihydro-1-methyl-1H-indole-2-carboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-Methyl-2,3-Dihydro-1H-Indole-2-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.