Description

2-(2-T-Boc-Aminoethoxy)Anisole-D3 is a deuterated, Boc-protected aniline derivative, a high-purity synthetic intermediate of significant value in advanced research and development. Its core value lies in the strategic incorporation of deuterium atoms, which enhances metabolic stability and pharmacokinetic properties in target molecules. This compound is essential for medicinal chemists and pharmaceutical researchers engaged in the synthesis of deuterated drug candidates, isotope labeling studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of deuterated active pharmaceutical ingredients (APIs) and drug candidates.
• Isotope Labeling Agent: Used in metabolic studies, pharmacokinetic (PK) research, and mass spectrometry to create internal standards and trace compounds.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by probing the effects of deuterium substitution on biological activity.
• Proteomics & Biomarker Discovery: Serves as a precursor for labeled reagents used in quantitative proteomics and biomarker analysis.
• Organic Synthesis Building Block: Utilized in multi-step syntheses requiring a protected aminoethoxy aniline moiety with isotopic labeling.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of isotopically labeled compounds.

Basic Information

Item	Detail
Product Name	2-(2-T-Boc-Aminoethoxy)Anisole-D3
CAS No.	1219179-77-7
Molecular Formula	C14H18D3NO4
Molecular Weight	Contact for details
Synonyms	2-(2-((Tert-Butoxycarbonyl)amino)ethoxy)anisole-d3; 1-Methoxy-2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]benzene-d3; 2-(2-(Boc-amino)ethoxy)anisole-d3; Boc-AEEA-Anisole-d3; tert-Butyl N-[2-(2-methoxyphenoxy)ethyl]carbamate-d3; Deuterated Boc-protected aminoethoxy anisole; (2-Methoxyphenoxy)ethyl Boc-amine-d3
EINECS	Contact for details

Quality Control

Our 2-(2-T-Boc-Aminoethoxy)Anisole-D3 is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analytical characterization, including NMR (¹H, ¹³C), HPLC, and Mass Spectrometry, to confirm chemical structure, deuterium incorporation, and purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this moisture-sensitive material from atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.