Description

Rac Cycloserine-15N,D3 is a stable isotope-labeled analog of the antibiotic Cycloserine, specifically incorporating nitrogen-15 and deuterium atoms. This compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway elucidation in mass spectrometry-based studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) research, proteomics, and biomarker discovery.

Application

• Internal Standard for LC-MS/MS: Serves as a critical reference compound for the accurate quantification of Cycloserine and its metabolites in complex biological matrices like plasma, urine, and tissue homogenates.
• Drug Metabolism Studies (DMPK): Used in absorption, distribution, metabolism, and excretion (ADME) research to trace and understand the metabolic fate of the parent drug.
• Proteomics & Biomarker Research: Facilitates stable isotope labeling techniques for relative and absolute protein quantification (SILAC, AQUA).
• Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling: Enables precise measurement of drug concentration over time to establish dose-response relationships.
• Forensic & Anti-Doping Analysis: Provides a definitive standard for confirmatory testing in forensic toxicology and sports anti-doping controls.
• Quality Control & Method Development: Essential for developing, validating, and ensuring the robustness of analytical methods in regulatory environments.

Basic Information

Product Name	Rac Cycloserine-15N,D3
CAS No.	1219176-26-7
Molecular Formula	C3H2D315N3O2
Molecular Weight	~105.09 g/mol
Synonyms	(±)-4-Amino-3-isoxazolidinone-15N,D3; D-Cycloserine-15N,D3 (racemic); Racemic Cycloserine-15N,D3; (RS)-Cycloserine-15N,D3; 4-Amino-1,2-oxazolidin-3-one-15N,D3 (racemic); Oxamycin-15N,D3 (racemic); Seromycin-15N,D3 (racemic)
EINECS	Contact for details

Quality Control

Every batch of Rac Cycloserine-15N,D3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment, and impurity profiling via advanced techniques like NMR and LC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes to support your regulatory submissions and ensure data integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment (15N)	≥98 atom %
Isotopic Enrichment (D)	≥98 atom % D (D3)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.