Description

6-Bromo-3-Methyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the isoquinolinone class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new pharmacophores.
• Agrochemical Development: Serves as a building block for creating new pesticides and herbicides with specific modes of action.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex heterocyclic frameworks via cross-coupling and functional group transformations.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental research in organic chemistry and drug discovery.

Basic Information

Product Name	6-Bromo-3-Methyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1219130-51-4
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	6-Bromo-3-methyl-1,2,3,4-tetrahydroisoquinolin-1-one; 6-Bromo-3-methyl-3,4-dihydro-1H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 6-bromo-3-methyl-3,4-dihydro-; 6-Bromo-3-methyl-1,2,3,4-tetrahydroisoquinoline-1-one; 6-Bromo-3-methyl-3,4-dihydroisoquinolin-1(2H)-one; 1219130-51-4
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Methyl-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results. We are committed to meeting the stringent requirements of cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.