Description

1-Isoquinolylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing isoquinoline-containing drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Research: Used to create novel heterocyclic compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science: Building block for constructing organic semiconductors, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Enables the labeling and modification of biomolecules for diagnostic and research tools.
• Academic & Contract Research: Fundamental reagent for methodological development and library synthesis in academic and CRO laboratories.

Basic Information

Product Name	1-Isoquinolylboronic Acid
CAS No.	1219080-58-6
Molecular Formula	C9H8BNO2
Molecular Weight	173.98 g/mol
Synonyms	Isoquinolin-1-ylboronic Acid; 1-Boronoisoquinoline; (Isoquinolin-1-yl)boronic Acid; 1-Isoquinolineboronic Acid; B-(1-Isoquinolyl)boronic Acid; 1-Quinolinylboronic Acid (common misnomer); 1219080-58-6; Isoquinoline-1-boronic acid
EINECS	Contact for details

Quality Control

Our 1-Isoquinolylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades are available to support your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.