Description

3-Carbamoyl-1-Methyl-D3-Pyridinium Chloride is a high-purity, isotopically labeled pyridinium salt, specifically deuterated on the methyl group. This compound is essential for advanced analytical research and development, particularly in the fields of mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It serves as a critical internal standard, reference material, or synthetic intermediate for scientists and manufacturers in the pharmaceutical, agrochemical, and academic research sectors.

Application

• Internal Standard for LC-MS/MS: Used as a stable isotope-labeled internal standard (SIL-IS) in quantitative bioanalytical methods for drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolite Identification: Aids in the identification and quantification of metabolites in complex biological matrices through mass spectrometry.
• NMR Spectroscopy: Serves as a deuterated reference compound or a precursor for synthesizing other labeled molecules for structural analysis.
• Pharmaceutical R&D: Employed in the development and validation of analytical methods for new chemical entities (NCEs) and generic drugs.
• Chemical Synthesis: Acts as a specialized building block for the synthesis of more complex deuterated compounds.
• Quality Control & Method Development: Used in analytical laboratories to ensure method accuracy, precision, and compliance with regulatory guidelines.

Basic Information

Product Name	3-Carbamoyl-1-Methyl-D3-Pyridinium Chloride
CAS No.	1218993-18-0
Molecular Formula	C7H6D3ClN2O
Molecular Weight	175.62 g/mol
Synonyms	1-Methyl-3-carbamoylpyridinium-d3 chloride; Nicotinamide-d3 N-methyl chloride; 3-Carbamoyl-N-methyl-d3-pyridinium chloride; Deuterated N-Methylnicotinamide Chloride; N-Methylnicotinamide-d3 chloride; Pyridinium, 3-carbamoyl-1-methyl-d3-, chloride; 1-Methyl-3-pyridinecarboxamide-d3 chloride
EINECS	Contact for details

Quality Control

Our 3-Carbamoyl-1-Methyl-D3-Pyridinium Chloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, chemical purity, and isotopic enrichment. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.