Description

3-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid is a high-purity, synthetically valuable boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic coupling.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex organic molecules.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, dyes, and advanced performance materials.

Basic Information

Product Name	3-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid
CAS No.	1218791-11-7
Molecular Formula	C13H16BNO6
Molecular Weight	293.08 g/mol
Synonyms	2-(3-Nitro-4-carboxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-nitrobenzoic Acid; 3-Nitro-4-(pinacolatoboryl)benzoic Acid; Benzoic acid, 3-nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol 3-Nitro-4-boronobenzoate; 3-Nitro-4-boronobenzoic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.