Description

2-(3-Methoxybenzoyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of central nervous system (CNS) and cardiovascular drug discovery. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting specific receptors or enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic compounds.
• Preclinical Development: Serves as a critical material for producing batches of active pharmaceutical ingredients (APIs) for early-stage toxicology and pharmacology studies.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and validation in quality control laboratories.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2-(3-Methoxybenzoyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	1218664-35-7
Molecular Formula	C18H17NO4
Molecular Weight	311.33 g/mol
Synonyms	2-(3-Methoxybenzoyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 1,2,3,4-Tetrahydro-2-(3-methoxybenzoyl)-3-isoquinolinecarboxylic acid; 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(3-methoxybenzoyl)-; 1218664-35-7; 2-(3-Methoxybenzoyl)-3-carboxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 2-(3-Methoxybenzoyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We can supply material suitable for research use or under more stringent quality agreements for development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.