Description

Ethyl 3-{[(1E)-(Dimethylamino)Methylene]Amino}-5-Methoxy-1-Methyl-1H-Indole-2-Carboxylate is a sophisticated heterocyclic building block and advanced pharmaceutical intermediate of significant interest in synthetic organic chemistry. Its core value lies in its functionalized indole scaffold, which serves as a versatile precursor for the synthesis of complex molecules, particularly in medicinal chemistry programs. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing novel active ingredients, such as kinase inhibitors or other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides that require complex heterocyclic cores.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and protein functions.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex indole-based natural product analogs or functional materials.

Basic Information

Product Name	Ethyl 3-{[(1E)-(Dimethylamino)Methylene]Amino}-5-Methoxy-1-Methyl-1H-Indole-2-Carboxylate
CAS No.	1217885-75-0
Molecular Formula	C₁₆H₂₁N₃O₃
Molecular Weight	303.36 g/mol
Synonyms	Ethyl 3-[(dimethylamino)methylideneamino]-5-methoxy-1-methyl-1H-indole-2-carboxylate; (E)-Ethyl 3-((dimethylamino)methyleneamino)-5-methoxy-1-methyl-1H-indole-2-carboxylate; 5-Methoxy-1-methyl-1H-indole-2-carboxylic acid ethyl ester 3-[(dimethylamino)methylene]hydrazone; CAS 1217885-75-0; VINYLAMINE INTERMEDIATE; Advanced Indole Derivative; Pharmaceutical Building Block 1217885-75-0
EINECS	Contact for details

Quality Control

Our Ethyl 3-{[(1E)-(Dimethylamino)Methylene]Amino}-5-Methoxy-1-Methyl-1H-Indole-2-Carboxylate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.