Description

{2-[Dimethyl(4-Phenylphenyl)Silyl]Phenyl}Methanol is a specialized organosilicon intermediate featuring a bifunctional structure with both a silyl-protecting group and a reactive hydroxymethyl moiety. This compound matters for its utility in advanced organic synthesis, particularly in the construction of complex molecules where selective protection and subsequent functionalization are required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in medicinal chemistry and the synthesis of novel silicon-containing polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates requiring silicon incorporation or specific protecting group strategies.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the silyl group modulates bioavailability and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty silicones, resins, and advanced polymeric materials with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories as a versatile reagent for introducing the dimethyl(4-phenylphenyl)silyl group, a useful protecting group for alcohols and other functionalities.
• Ligand and Catalyst Development: Potential precursor for creating novel ligands or organosilicon catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	{2-[Dimethyl(4-Phenylphenyl)Silyl]Phenyl}Methanol
CAS No.	1217863-72-3
Molecular Formula	C21H22OSi
Molecular Weight	318.49 g/mol
Synonyms	[2-[Dimethyl(biphenyl-4-yl)silyl]phenyl]methanol; (2-Hydroxymethylphenyl)dimethyl(4-phenylphenyl)silane; [2-(Dimethyl-[1,1'-biphenyl]-4-yl-silyl)phenyl]methanol; Dimethyl[4-phenylphenyl]silyl-2-benzyl alcohol; Biphenyl-4-yldimethyl(2-(hydroxymethyl)phenyl)silane; (2-(Dimethyl(biphenyl-4-yl)silyl)phenyl)methanol
EINECS	Contact for details

Quality Control

Our {2-[Dimethyl(4-Phenylphenyl)Silyl]Phenyl}Methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.