Description

1H-Indole-2-Carboxylic Acid, 5-Bromo-3-Phenyl-, Methyl Est is a high-purity, synthetically valuable brominated indole derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Used in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its indole core.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.
• Bioconjugation & Probe Development: Serves as a starting material for creating fluorescent probes or affinity labels for biochemical and diagnostic applications.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 5-Bromo-3-Phenyl-, Methyl Est
CAS No.	1217862-75-3
Molecular Formula	C16H12BrNO2
Molecular Weight	330.18 g/mol
Synonyms	Methyl 5-bromo-3-phenyl-1H-indole-2-carboxylate; 5-Bromo-3-phenyl-1H-indole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 5-bromo-3-phenyl-, methyl ester; 5-Bromo-3-phenylindole-2-carboxylic acid methyl ester; Methyl 5-bromo-3-phenylindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Carboxylic Acid, 5-Bromo-3-Phenyl-, Methyl Est adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP compliance for advanced intermediate manufacturing, and we are committed to meeting the specific quality requirements of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.